Human-Based Platelet Lysates (PL)
Derived from human platelets through controlled processing, PL is rich in growth factors and proteins essential for wound healing and tissue regeneration. Within InterLynk, PL is integrated into biomaterial formulations to enhance bioactivity, promote cell recruitment, and support tissue repair. Methacrylated (MA) modifications allow for fine-tuned mechanical properties and controlled release of bioactive molecules, ensuring stability and structural integrity in multimaterial scaffolds.
Double-Network Hydrogels
Designed to mimic soft tissues, these hydrogels combine high water content with robust mechanical properties. Their dual-network structure provides enhanced resilience, making them suitable for load-bearing applications. Additionally, they serve as carriers for therapeutic molecules, enabling localized and sustained drug delivery for improved regeneration outcomes.
Calcium Phosphate (CaP)
A gold standard for bone regeneration, CaP-based ceramics offer excellent osteoconductivity and compositional similarity to natural bone. Within InterLynk, innovative sintering-free formulations are being developed to improve processability and mechanical performance. The incorporation of CaP particles mimics native bone microstructures, reinforcing scaffolds while maintaining bioactivity.
Methacrylated PCL-LA Copolymers
Electrospun fibers made from methacrylated poly(caprolactone-lactic acid) (PCL-LA) copolymers provide both flexibility and mechanical reinforcement. Their ability to integrate seamlessly with other biomaterials makes them ideal for constructing multi-tissue interfaces. When combined with CaP particles, they further enhance scaffold strength and osteogenic potential.
Flavonoid-Loaded Nanocarriers
Nanoscale drug delivery systems, such as Naringin-loaded micelles, introduce bioactive compounds with anti-inflammatory and pro-osteogenic properties. These nanocarriers enable precise, sustained drug release, enhancing the therapeutic potential of InterLynk scaffolds while supporting bone regeneration and reducing inflammation.